HitPredict

Interactor 1: SEPT2 (Q15019)
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)
Gene: SEPTIN2

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26496610, 31586073, 36526897
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0015629 - actin cytoskeleton GO:0030496 - midbody GO:0045296 - cadherin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 1124
+	Hs
		1080984 SEPT7_HUMAN (11-357): 2.78e-171: 485: 53.61		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1267803 SEPT8_HUMAN (3-348): 2.74e-162: 464: 39.54		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343753 SEPT9_HUMAN (2-320): 2.97e-159: 460: 45.68		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343678 SEP11_HUMAN (8-348): 3.99e-161: 459: 39.83		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1049014 SEPT6_HUMAN (14-348): 5.19e-160: 457: 40.24		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343728 SEP10_HUMAN (14-357): 7.49e-159: 454: 38.00		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		91558 E7EW69_HUMAN (14-357): 9.37e-159: 454: 38.00		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		776977 PNUT_DROME (6-347): 2.55e-175: 499: 51.60		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84
+	Dm
		870191 SEPT2_DROME (2-357): 4.01e-156: 446: 40.06		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84
+	Dm
		1180701 Q7KLG8_DROME (1-348): 1.07e-154: 443: 40.62		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84