HitPredict

Interactor 1: SART3 (Q15020)
Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein)
Gene: SART3

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.828

Property	Details
Experiments	27990632, 11477570
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti bait coimmunoprecipitation, confocal microscopy
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0016607 - nuclear speck GO:0061574 - ASAP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 963 Hs			1 305
+	Hs
		1063203 SART3_HUMAN (1-963): 0: 638: 100.00		SART3_HUMAN (2-302): 1.67e-38: 146: 16.32
+	Hs
		1070619 CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		1318165 CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		300152 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		300288 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		1022281 CSTF3_HUMAN (88-585): 1.96e-82: 283: 16.18		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		300087 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Sc
		996591 CLF1_YEAST (48-658): 1.77e-74: 260: 13.68		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Sc
		628773 RNA14_YEAST (80-577): 3.25e-70: 248: 13.43		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Sc
		763253 PRP39_YEAST (130-596): 1.57e-67: 239: 13.25		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		641791 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Hs
		198842 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		516364 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32
+	Hs
		641756 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		PABP4_HUMAN (153-248): 4.98e-19: 89.2: 27.08
+	Sc
		648449 NSR1_YEAST (693-880): 1.88e-48: 180: 28.50		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		1031507 PABP4_HUMAN (605-903): 3.97e-45: 175: 17.67		RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38
+	Hs
		853881 PABP4_HUMAN (605-903): 3.97e-45: 175: 17.67		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Hs
		516495 PABP4_HUMAN (605-903): 3.97e-45: 175: 17.67		PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32
+	Hs
		474021 PABP4_HUMAN (605-903): 3.97e-45: 175: 17.67		PAB4L_HUMAN (161-242): 1.56e-18: 86.5: 30.49
+	Hs
		516339 PABP1_HUMAN (694-885): 5.86e-38: 153: 21.13		PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32