HitPredict

Interactor 1: SUZ12 (Q15022)
Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog)
Gene: SUZ12

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24457600, 19734898
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031490 - chromatin DNA binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 372
+	Hs
		260886 SUZ12_HUMAN (68-739): 0: 1081: 100.00		H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31
+	Hs
		555468 SUZ12_HUMAN (68-739): 0: 1081: 100.00		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		1063481 SUZ12_HUMAN (68-739): 0: 1081: 100.00		H2A2B_HUMAN (1-123): 1.24e-64: 203: 63.49
+	Hs
		1063449 SUZ12_HUMAN (68-739): 0: 1081: 100.00		H2A2A_HUMAN (1-126): 4.27e-64: 201: 62.02
+	Hs
		391711 SUZ12_HUMAN (68-739): 0: 1081: 100.00		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		1063428 SUZ12_HUMAN (68-739): 0: 1081: 100.00		PAR14_HUMAN (152-370): 1.01e-20: 96: 18.27