HitPredict

Interactor 1: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.701

The method score is based on:

Property Details
Experiments 30561431, 20010814, 18212736, 21988832
Identification Methods affinity chromatography technology, two hybrid, virotrap, two hybrid array, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 636
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024