HitPredict

Interactor 1: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 28515276, 16723661
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EFG_C~EFG_C, EFG_C~EFG_III, EFG_C~EFG_IV, EFG_C~GTP_EFTU, EFG_III~EFG_IV, EFG_III~EFTUD2, EFG_III~GTP_EFTU, EFG_III~GTP_EFTU_D2, EFG_IV~GTP_EFTU, EFTUD2~GTP_EFTU, EFTUD2~GTP_EFTU_D2, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D2
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
and 13 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 972
Hs

1 972
+ Hs
+ Sp
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024