HitPredict

Interactor 1: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0016607 - nuclear speck
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 972 Hs			1 471
+	Hs
		1031337 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		1064530 U5S1_HUMAN (1-972): 0: 1062: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516526 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		613461 U5S1_HUMAN (1-972): 0: 1062: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Sp
		292934 SN114_SCHPO (1-970): 0: 928: 54.22		PABP_SCHPO (2-471): 9.26e-65: 222: 14.98
+	Hs
		1064471 U5S1_HUMAN (1-972): 0: 1062: 100.00		RAVR1_HUMAN (76-221): 8.34e-12: 69.4: 24.70
+	Hs
		1064676 U5S1_HUMAN (1-972): 0: 1062: 100.00		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71