HitPredict

Interactor 1: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Interactor 2: SF3B4 (Q15427)
Splicing factor 3B subunit 4 (Pre-mRNA-splicing factor SF3b 49 kDa subunit) (Spliceosome-associated protein 49) (SAP 49)
Gene: SF3B4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	22365833, 28515276
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071005 - U2-type precatalytic spliceosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 972 Hs			1 424
+	Hs
		1048067 U5S1_HUMAN (1-972): 0: 1062: 100.00		HNRPD_HUMAN (3-273): 4.01e-55: 188: 19.12
+	Hs
		1031337 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP4_HUMAN (4-188): 5.81e-40: 153: 38.17
+	Hs
		516526 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP1_HUMAN (90-181): 1.18e-11: 68.7: 27.17
+	Hs
		531150 EF2_HUMAN (111-957): 0: 915: 38.16		HNRPD_HUMAN (3-273): 4.01e-55: 188: 19.12
+	Sp
		292934 SN114_SCHPO (1-970): 0: 928: 54.22		PABP_SCHPO (97-187): 9.16e-14: 75.2: 25.28
+	Sc
		731792 SN114_YEAST (3-967): 0: 692: 32.82		HSH49_YEAST (14-195): 7.65e-36: 132: 37.76