HitPredict

Interactor 1: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27173435, 28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EFTUD2~WD40
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck GO:0071005 - U2-type precatalytic spliceosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 972 Hs			1 513
+	Hs
		903237 U5S1_HUMAN (1-972): 0: 1062: 100.00		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		1064590 U5S1_HUMAN (1-972): 0: 1062: 100.00		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		531105 EF2_HUMAN (111-957): 0: 915: 38.16		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		929471 U5S1_HUMAN (1-972): 0: 1062: 100.00		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		531113 EF2_HUMAN (111-957): 0: 915: 38.16		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33