HitPredict

Interactor 1: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28515276, 28561026, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 972 Hs			1 456
+	Hs
		1064850 U5S1_HUMAN (1-972): 0: 1062: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Sc
		687474 EF2_YEAST (111-957): 0: 879: 36.04		RUVB1_YEAST (1-455): 0: 652: 67.39
+	Sc
		687515 EF2_YEAST (111-957): 0: 879: 36.04		RUVB2_YEAST (5-455): 0: 627: 41.72