HitPredict

Interactor 1: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Interactor 2: SF3B6 (Q9Y3B4)
Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)
Gene: SF3B6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 972 Hs			1 125
+	Hs
		441289 U5S1_HUMAN (1-972): 0: 1062: 100.00		RU2B_HUMAN (16-111): 5.15e-38: 129: 25.00
+	Hs
		1064837 U5S1_HUMAN (1-972): 0: 1062: 100.00		PPIE_HUMAN (17-108): 4.08e-29: 108: 22.11
+	Hs
		1031337 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP4_HUMAN (12-99): 1.35e-22: 93.3: 22.47
+	Hs
		516526 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP1_HUMAN (20-99): 4.52e-21: 89.1: 23.46
+	Hs
		992780 U5S1_HUMAN (1-972): 0: 1062: 100.00		SRSF1_HUMAN (21-91): 3.36e-18: 79: 33.80
+	Hs
		446640 U5S1_HUMAN (1-972): 0: 1062: 100.00		SNRPA_HUMAN (11-93): 1.11e-10: 58.7: 22.62
+	Sp
		292955 SN114_SCHPO (1-970): 0: 928: 54.22		RU2B_SCHPO (19-96): 3.44e-25: 93.6: 29.27