Interactor 1: SETB1 (Q15047)
Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1)
Gene: SETDB1

Interactor 2: MCAF2 (Q5U623)
Activating transcription factor 7-interacting protein 2 (ATF7-interacting protein 2) (MBD1-containing chromatin-associated factor 2)
Gene: ATF7IP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.639

The method score is based on:

Property Details
Experiments 33961781, 15691849
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0090309 - positive regulation of DNA methylation-dependent heterochromatin formation
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1291
Hs

1 682
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024