HitPredict

Interactor 1: SETB1 (Q15047)
Histone-lysine N-methyltransferase SETDB1 (EC 2.1.1.366) (ERG-associated protein with SET domain) (ESET) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (Lysine N-methyltransferase 1E) (SET domain bifurcated 1)
Gene: SETDB1

Interactor 2: DAXX (Q9UER7)
Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
Gene: DAXX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29084956, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0010629 - negative regulation of gene expression
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1291 Hs			1 740
+	Mm
		103634 G5E8N3_MOUSE (1-1291): 0: 1333: 90.53		DAXX_MOUSE (1-740): 0: 953: 69.34
+	Hs
		203803 SUV91_HUMAN (658-972): 1.59e-70: 244: 22.56		DAXX_HUMAN (1-740): 0: 1010: 100.00
+	Hs
		1302966 SETB2_HUMAN (908-1291): 3.78e-32: 136: 20.45		DAXX_HUMAN (1-740): 0: 1010: 100.00