Interactor 1: G5EE37 (G5EE37)
Incenp-like protein ICP-1 (Inner centromere protein ARK-binding domain-containing protein)
Gene: icp-1

Interactor 2: AIR2 (O01427)
Aurora/IPL1-related protein kinase 2 (EC 2.7.11.1) (Serine/threonine-protein kinase aurora-B)
Gene: air-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 25073157, 12707312, 11050385, 12048181, 14704431, 18692475, 15916946, unassigned701
Identification Methods biochemical, enzymatic study, pull down, two hybrid, protein kinase assay, two hybrid pooling approach
Interaction Type association, direct interaction, phosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains INCENP_ARK-bind~Pkinase
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000281 - mitotic cytokinesis
GO:0000776 - kinetochore
GO:0005737 - cytoplasm
GO:0015630 - microtubule cytoskeleton
and 6 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 622
Ce

1 305
+ Ce
+ Hs
+ Xl
+ Hs
+ Xl
+ Xl
+ Hs
+ Rn
+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024