HitPredict

Interactor 1: RRS1 (Q15050)
Ribosome biogenesis regulatory protein homolog
Gene: RRS1

Interactor 2: RPF2 (Q9H7B2)
Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog)
Gene: RPF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

The method score is based on:

Property	Details
Experiments	28514442, 30021884, 33961781, 37071682
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Brix~RRS1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0008097 - 5S rRNA binding GO:0042273 - ribosomal large subunit biogenesis and 2 others more... GO:1901796 - regulation of signal transduction by p53 class mediator GO:1902570 - protein localization to nucleolus
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	365
Hs

1	306

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024