HitPredict

Interactor 1: IQCB1 (Q15051)
IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)
Gene: IQCB1

Interactor 2: K2C74 (Q7RTS7)
Keratin, type II cytoskeletal 74 (Cytokeratin-74) (CK-74) (Keratin-5c) (K5C) (Keratin-74) (K74) (Type II inner root sheath-specific keratin-K6irs4) (Type-II keratin Kb37)
Gene: KRT74

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21565611
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 598 Hs			1 529
+	Hs
		380616 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C1_HUMAN (105-471): 4.75e-164: 481: 66.21
+	Hs
		729093 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K22E_HUMAN (112-456): 3.26e-150: 446: 67.54
+	Mm
		1152730 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C1B_MOUSE (108-455): 1.63e-143: 426: 63.79
+	Mm
		1112091 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K22E_MOUSE (80-456): 2.17e-134: 407: 61.27
+	Hs
		1065961 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C78_HUMAN (78-470): 1.81e-132: 396: 58.78
+	Hs
		409078 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C8_HUMAN (112-480): 3.62e-130: 389: 58.81
+	Mm
		1157154 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C73_MOUSE (1-457): 3.41e-99: 311: 76.37
+	Mm
		1152850 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C72_MOUSE (1-529): 1.63e-93: 296: 66.54
+	Hs
		531576 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C5_HUMAN (1-456): 7.45e-82: 267: 58.68
+	Hs
		380479 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C6B_HUMAN (8-472): 3.98e-81: 265: 57.00
+	Hs
		821661 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C6C_HUMAN (8-472): 1.23e-80: 264: 57.00
+	Mm
		1206956 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C5_MOUSE (1-468): 3.57e-78: 258: 58.16
+	Mm
		1113324 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K22O_MOUSE (1-463): 9.89e-77: 254: 57.96
+	Hs
		359495 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C6A_HUMAN (8-472): 9.42e-78: 256: 57.20
+	Mm
		1152722 IQCB1_MOUSE (1-598): 0: 1069: 86.96		Q6IFT3_MOUSE (225-529): 1.87e-11: 68.7: 12.05