HitPredict

Interactor 1: IQCB1 (Q15051)
IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)
Gene: IQCB1

Interactor 2: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21565611
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 598 Hs			1 520
+	Mm
		376399 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C1_MOUSE (77-429): 1.39e-123: 377: 55.81
+	Mm
		1152730 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C1B_MOUSE (79-426): 4.07e-121: 369: 57.18
+	Hs
		729093 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K22E_HUMAN (83-427): 1.05e-121: 372: 55.65
+	Mm
		1112091 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K22E_MOUSE (83-427): 7.8e-117: 362: 54.78
+	Hs
		409078 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		380616 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Mm
		1152722 IQCB1_MOUSE (1-598): 0: 1069: 86.96		Q6IFT3_MOUSE (1-498): 1.34e-102: 327: 63.86
+	Mm
		1157154 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C73_MOUSE (1-516): 1.87e-91: 291: 47.37
+	Mm
		1152850 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C72_MOUSE (1-502): 1.44e-89: 285: 45.49
+	Hs
		380479 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C6B_HUMAN (76-448): 4.72e-80: 262: 59.25
+	Hs
		821661 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C6C_HUMAN (76-448): 1.24e-79: 261: 59.52
+	Mm
		1206956 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K2C5_MOUSE (76-439): 1.57e-77: 256: 61.26
+	Hs
		359495 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C6A_HUMAN (76-448): 1.02e-78: 258: 59.79
+	Hs
		531576 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C5_HUMAN (76-427): 3.19e-78: 258: 62.50
+	Hs
		1065949 IQCB1_HUMAN (1-598): 0: 1065: 100.00		K2C74_HUMAN (1-502): 1.03e-76: 252: 47.06
+	Mm
		1113324 IQCB1_MOUSE (1-598): 0: 1069: 86.96		K22O_MOUSE (75-456): 9.56e-72: 241: 57.29