HitPredict

Interactor 1: KIF14 (Q15058)
Kinesin-like protein KIF14
Gene: KIF14

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	31586073, 34079125, 35271311, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1648 Hs			1 1190
+	Hs
		990843 KIF14_HUMAN (1-1648): 0: 891: 100.00		ZO1_HUMAN (19-1187): 5.94e-133: 447: 36.80
+	Hs
		1021494 KIF14_HUMAN (1-1648): 0: 891: 100.00		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Hs
		1066390 KIF14_HUMAN (1-1648): 0: 891: 100.00		PALS1_HUMAN (455-886): 1.77e-39: 159: 19.67
+	Ce
		619838 UN104_CAEEL (357-1160): 1.12e-137: 468: 36.26		LIN2_CAEEL (212-890): 1.23e-94: 327: 14.79
+	Hs
		159161 KINH_HUMAN (356-1198): 1.07e-143: 470: 20.59		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Hs
		159121 KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Hs
		159288 KI26A_HUMAN (47-708): 5.21e-109: 387: 17.53		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Hs
		116734 KIF2A_HUMAN (163-845): 1.24e-108: 364: 20.90		CSKP_HUMAN (229-890): 6.3e-93: 321: 15.09
+	Mm
		702841 KIF5A_MOUSE (352-1231): 5.58e-145: 475: 20.80		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		660025 KIF3A_MOUSE (348-951): 4.89e-143: 459: 26.69		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		942384 KI13B_HUMAN (356-1164): 2.11e-131: 453: 33.45		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Mm
		93501 E9Q4K7_MOUSE (356-1163): 1.47e-127: 442: 33.05		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		1021567 KI13B_HUMAN (356-1164): 2.11e-131: 453: 33.45		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Hs
		231496 KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52		DLG4_HUMAN (3-423): 2.31e-52: 199: 18.89
+	Rn
		292059 KIF1B_RAT (354-1156): 5.21e-123: 428: 27.59		DLG4_RAT (3-423): 1.74e-52: 199: 18.89
+	Hs
		231509 KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52		DLG1_HUMAN (1-515): 2.7e-47: 185: 16.38
+	Rn
		292061 KIF1B_RAT (354-1156): 5.21e-123: 428: 27.59		DLG1_RAT (1-513): 8.04e-44: 174: 16.64
+	Mm
		660012 KIF2A_MOUSE (163-845): 1.33e-108: 364: 21.21		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Dm
		54780 A1ZA18_DROME (354-1161): 1.06e-116: 410: 34.22		DLG1_DROME (12-421): 3.86e-35: 147: 17.36