HitPredict

Interactor 1: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Interactor 2: TAF5 (Q15542)
Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100)
Gene: TAF5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 726 Hs			1 800
+	Hs
		631433 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		TAF5_HUMAN (1-800): 0: 655: 100.00
+	Hs
		1074790 BRDT_HUMAN (18-695): 2.15e-107: 350: 49.71		TAF5_HUMAN (1-800): 0: 655: 100.00
+	Hs
		631541 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		FBXW7_HUMAN (513-795): 2.58e-75: 260: 26.21
+	Sc
		744679 GCN5_YEAST (284-417): 7.13e-37: 145: 31.88		TAF5_YEAST (136-799): 1.3e-128: 404: 28.26
+	Hs
		267783 KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86		TAF5L_HUMAN (183-795): 4.06e-110: 350: 34.09
+	Hs
		267784 KAT2B_HUMAN (267-414): 8.8e-32: 134: 25.50		TAF5L_HUMAN (183-795): 4.06e-110: 350: 34.09
+	Hs
		1281472 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		FBXW7_HUMAN (513-795): 2.58e-75: 260: 26.21
+	Dm
		1362904 Q9VCG6_DROME (273-565): 1.87e-20: 97.6: 15.36		Q9VT91_DROME (201-792): 3.27e-102: 338: 27.81
+	Hs
		243688 BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56		TBL1X_HUMAN (538-798): 4.59e-69: 240: 19.21
+	Sp
		252179 YK82_SCHPO (29-148): 6.59e-30: 128: 33.61		NLE1_SCHPO (576-799): 6.08e-57: 204: 21.11
+	Dm
		1363034 Q9VTZ1_DROME (267-415): 9.98e-35: 143: 29.61		Q9VCN9_DROME (236-662): 6.33e-48: 184: 15.21
+	Dm
		1358857 Q9VTZ1_DROME (267-415): 9.98e-35: 143: 29.61		WDS_DROME (660-799): 5.37e-41: 156: 21.43
+	Sp
		251276 YK82_SCHPO (29-148): 6.59e-30: 128: 33.61		TAF73_SCHPO (620-796): 3.79e-42: 165: 21.47
+	Mm
		1265132 KAT2A_MOUSE (267-414): 7.42e-33: 137: 28.86		TAF5L_MOUSE (589-799): 1.39e-34: 142: 19.27
+	Hs
		903172 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		WDR5_HUMAN (699-800): 6.52e-24: 105: 21.10
+	Hs
		903408 KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86		WDR5_HUMAN (699-800): 6.52e-24: 105: 21.10
+	Mm
		903679 KAT2A_MOUSE (267-414): 7.42e-33: 137: 28.86		WDR5_MOUSE (699-800): 6.52e-24: 105: 21.10
+	Hs
		903409 KAT2B_HUMAN (267-414): 8.8e-32: 134: 25.50		WDR5_HUMAN (699-800): 6.52e-24: 105: 21.10
+	Sp
		140401 YK82_SCHPO (29-148): 6.59e-30: 128: 33.61		TAF5_SCHPO (661-798): 1.57e-18: 92.5: 17.22
+	Hs
		244210 BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56		WDR5_HUMAN (699-800): 6.52e-24: 105: 21.10