HitPredict

Interactor 1: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Interactor 2: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 726 Hs			1 130
+	Hs
		1067038 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62
+	Hs
		1066979 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Hs
		555470 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Hs
		391554 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		631492 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62
+	Hs
		555299 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Sc
		392513 RSC1_YEAST (39-723): 1.84e-59: 218: 14.40		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Hs
		391965 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		555690 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Sc
		392580 RSC2_YEAST (63-660): 6.42e-45: 175: 13.13		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Hs
		391671 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Mm
		70932 EP300_MOUSE (4-177): 2.63e-34: 143: 22.86		H2A3_MOUSE (1-130): 6.2e-67: 199: 97.69
+	Sc
		392211 RSC2_YEAST (63-660): 6.42e-45: 175: 13.13		H2A1_YEAST (16-127): 2.97e-53: 165: 81.25
+	Hs
		998866 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		H2A2B_HUMAN (1-130): 1.54e-65: 196: 94.62
+	Hs
		391824 KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86		H2A1B_HUMAN (1-130): 9.51e-67: 199: 96.92
+	Hs
		998781 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		H2A2C_HUMAN (1-128): 2.7e-64: 193: 96.88
+	Hs
		555430 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Hs
		555569 KAT2A_HUMAN (267-414): 1.15e-33: 140: 28.86		H2AX_HUMAN (1-130): 3.33e-63: 190: 88.81
+	Sc
		392549 GCN5_YEAST (284-417): 7.13e-37: 145: 31.88		H2A2_YEAST (16-128): 5.91e-59: 179: 80.53
+	Sc
		392189 GCN5_YEAST (284-417): 7.13e-37: 145: 31.88		H2A1_YEAST (16-127): 2.97e-53: 165: 81.25