HitPredict

Interactor 1: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 726 Hs			1 1214
+	Hs
		1067081 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		631516 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		631538 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		1123381 BRDT_HUMAN (18-695): 2.15e-107: 350: 49.71		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		1123386 BRDT_HUMAN (18-695): 2.15e-107: 350: 49.71		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		998902 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		998950 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Sc
		797921 RSC1_YEAST (39-723): 1.84e-59: 218: 14.40		RSC8_YEAST (336-751): 4.61e-104: 342: 28.30
+	Sc
		797956 RSC2_YEAST (63-660): 6.42e-45: 175: 13.13		RSC8_YEAST (336-751): 4.61e-104: 342: 28.30
+	Sc
		797934 GCN5_YEAST (284-417): 7.13e-37: 145: 31.88		RSC8_YEAST (336-751): 4.61e-104: 342: 28.30
+	Sc
		696166 GCN5_YEAST (284-417): 7.13e-37: 145: 31.88		SWI3_YEAST (254-793): 1.23e-96: 329: 26.48
+	Mm
		1112509 Q3UH28_MOUSE (3-705): 1.82e-51: 195: 12.76		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Hs
		232586 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		232126 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		261515 ZMY11_HUMAN (3-446): 1.03e-44: 171: 9.63		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		999262 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261484 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		1350536 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		RERE_HUMAN (759-1212): 1.19e-09: 65: 16.17
+	Hs
		999163 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		RERE_HUMAN (759-1212): 1.19e-09: 65: 16.17
+	Mm
		70941 KAT2A_MOUSE (267-414): 7.42e-33: 137: 28.86		EP300_MOUSE (885-1214): 8.74e-09: 62.4: 13.78