HitPredict

Interactor 1: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 726 Hs			1 601
+	Hs
		631620 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		HMGX4_HUMAN (1-601): 0: 813: 100.00
+	Hs
		1067030 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		996682 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		631488 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		631411 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		175778 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		HMGB3_HUMAN (411-495): 5.79e-12: 67.2: 21.84
+	Sc
		705899 RSC1_YEAST (39-723): 1.84e-59: 218: 14.40		IXR1_YEAST (316-512): 2.11e-35: 143: 16.81
+	Hs
		818600 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Hs
		996954 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Sc
		705910 RSC2_YEAST (63-660): 6.42e-45: 175: 13.13		IXR1_YEAST (316-512): 2.11e-35: 143: 16.81
+	Hs
		1071474 ZMY11_HUMAN (3-446): 1.03e-44: 171: 9.63		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Sc
		514196 RSC1_YEAST (39-723): 1.84e-59: 218: 14.40		NHP6A_YEAST (394-476): 2.15e-14: 71: 29.41
+	Hs
		818793 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		SOX9_HUMAN (337-527): 1.69e-32: 133: 14.43
+	Hs
		817978 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Hs
		1300993 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		225734 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		SOX15_HUMAN (363-554): 8.83e-31: 122: 14.49
+	Hs
		1349877 ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21		HM20B_HUMAN (386-479): 3.62e-12: 69.5: 24.74
+	Hs
		449701 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Sc
		514213 RSC2_YEAST (63-660): 6.42e-45: 175: 13.13		NHP6A_YEAST (394-476): 2.15e-14: 71: 29.41
+	Hs
		643336 EP300_HUMAN (4-177): 1.2e-34: 144: 22.86		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56