HitPredict

Interactor 1: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain, Bromodomain~PHD
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0070577 - lysine-acetylated histone binding GO:0071168 - protein localization to chromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 726 Hs			1 1186
+	Hs
		631631 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		331815 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		1067099 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		NSD1_HUMAN (12-358): 2.19e-51: 201: 15.98
+	Hs
		1067068 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		1067123 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		NSD3_HUMAN (3-359): 2.43e-44: 177: 14.64
+	Hs
		331723 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		170259 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		631525 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		1067156 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		BAZ1A_HUMAN (5-252): 1.74e-36: 152: 14.63
+	Hs
		1017300 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		631576 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		NSD3_HUMAN (3-359): 2.43e-44: 177: 14.64
+	Hs
		631624 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		600145 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		631413 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		1067030 BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		1123391 BRDT_HUMAN (18-695): 2.15e-107: 350: 49.71		NSD3_HUMAN (3-359): 2.43e-44: 177: 14.64
+	Hs
		600081 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		631488 BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Sc
		975973 RSC2_YEAST (63-660): 6.42e-45: 175: 13.13		GCN5_YEAST (120-252): 1.1e-33: 137: 23.88
+	Sc
		728765 RSC2_YEAST (63-660): 6.42e-45: 175: 13.13		BDF1_YEAST (122-265): 3.31e-23: 108: 14.77