HitPredict

Interactor 1: G5EE67 (G5EE67)
Skp1-related protein
Gene: skr-3

Interactor 2: CUL6 (Q21346)
Cullin-6
Gene: cul-6

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11864567
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cullin~Skp1_POZ
Common GO terms	GO:0016567 - protein ubiquitination GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 167 Ce			1 729
+	Mm
		1376703 SKP1_MOUSE (8-167): 1.7e-78: 232: 53.99		CUL1_MOUSE (1-729): 0: 778: 35.03
+	Hs
		928899 SKP1_HUMAN (8-167): 3.25e-78: 231: 53.99		CUL1_HUMAN (1-729): 0: 779: 35.03
+	Hs
		928901 SKP1_HUMAN (8-167): 3.25e-78: 231: 53.99		CUL3_HUMAN (3-729): 0: 746: 24.81
+	Hs
		928902 SKP1_HUMAN (8-167): 3.25e-78: 231: 53.99		CUL4A_HUMAN (4-729): 0: 739: 27.53
+	Ce
		105467 SKR1_CAEEL (1-167): 3.89e-78: 231: 54.12		CUL1_CAEEL (2-729): 0: 732: 47.09
+	Hs
		928903 SKP1_HUMAN (8-167): 3.25e-78: 231: 53.99		CUL4B_HUMAN (4-729): 0: 723: 27.94
+	Ce
		106724 G5EE67_CAEEL (1-167): 1.07e-73: 220: 100.00		CUL1_CAEEL (2-729): 0: 732: 47.09
+	At
		1277333 ASK4_ARATH (4-165): 4.76e-73: 218: 40.12		CUL1_ARATH (1-729): 0: 722: 25.69
+	Ce
		105999 G5EDD8_CAEEL (2-167): 1.93e-68: 207: 52.10		CUL1_CAEEL (2-729): 0: 732: 47.09
+	At
		1277346 ASK3_ARATH (4-165): 1.71e-71: 214: 38.32		CUL1_ARATH (1-729): 0: 722: 25.69
+	Hs
		928900 SKP1_HUMAN (8-167): 3.25e-78: 231: 53.99		CUL2_HUMAN (1-729): 0: 705: 29.45
+	Dm
		284976 O77430_DROME (8-167): 3.2e-72: 216: 49.69		CUL1_DROME (1-729): 0: 717: 35.15
+	At
		221655 ASK11_ARATH (6-165): 8.34e-70: 209: 47.50		CUL1_ARATH (1-729): 0: 722: 25.69
+	Dm
		284981 O77430_DROME (8-167): 3.2e-72: 216: 49.69		Q5BI50_DROME (5-729): 0: 715: 27.55
+	At
		1107618 SKP1A_ARATH (6-165): 4.35e-69: 208: 45.12		CUL1_ARATH (1-729): 0: 722: 25.69
+	At
		1277329 SKP1B_ARATH (8-165): 5.31e-67: 203: 42.44		CUL1_ARATH (1-729): 0: 722: 25.69
+	At
		1277337 ASK10_ARATH (6-164): 3.71e-67: 202: 39.62		CUL1_ARATH (1-729): 0: 722: 25.69
+	Dm
		1097192 Q7KJ69_DROME (8-167): 2.56e-68: 206: 49.08		CUL1_DROME (1-729): 0: 717: 35.15
+	Sp
		142922 SKP1_SCHPO (9-167): 1.98e-69: 208: 45.73		CUL1_SCHPO (2-729): 0: 701: 30.49
+	Hs
		929020 SKP1_HUMAN (8-167): 3.25e-78: 231: 53.99		CUL5_HUMAN (1-729): 0: 610: 24.97