HitPredict

Interactor 1: EEA1 (Q15075)
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)
Gene: EEA1

Interactor 2: EEA1 (Q15075)
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)
Gene: EEA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.885

The method score is based on:

Property Details
Experiments 29568061, 11741531, 10024533, 21556036
Identification Methods proximity labelling technology, affinity chromatography technology, x-ray crystallography, two hybrid, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE~FYVE
Common GO terms GO:0005516 - calmodulin binding
GO:0005545 - 1-phosphatidylinositol binding
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0005969 - serine-pyruvate aminotransferase complex
and 16 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1411
Hs

1 1411
+ Zm
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+ Hs
+ Hs
+ Hs
+ Rn
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+ Hs
+ Hs
+ Hs
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+ Mm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024