HitPredict

Interactor 1: KPCD1 (Q15139)
Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
Gene: PRKD1

Interactor 2: KPCD2 (Q9BZL6)
Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)
Gene: PRKD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 33961781, 35271311, 36652389
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~PH, C1_1~Pkinase, PH~PH, PH~Pkinase, Pkinase~Pkinase
Common GO terms GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0005080 - protein kinase C binding
and 21 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 912
Hs

1 878
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024