HitPredict

Interactor 1: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Interactor 2: PAN2 (Q504Q3)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19615732, 23398456
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 4684 Hs			1 1202
+	Hs
		1068624 PLEC_HUMAN (1-4684): 0: 1783: 100.00		UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02
+	Hs
		963343 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		PAN2_HUMAN (1-1202): 0: 1136: 100.00
+	Hs
		271077 ACTN3_HUMAN (166-893): 2.36e-146: 484: 25.79		UBP2_HUMAN (347-863): 2.12e-80: 278: 12.64
+	Hs
		271026 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		UBP2_HUMAN (347-863): 2.12e-80: 278: 12.64
+	Hs
		1059249 GOGB1_HUMAN (2666-3718): 4.33e-13: 78.9: 11.65		UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02
+	Hs
		974121 DYST_HUMAN (4185-4600): 1.51e-10: 70.4: 18.51		UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02
+	Hs
		1273964 MACF1_HUMAN (3704-4616): 3.72e-10: 69.3: 14.92		UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02
+	Hs
		551797 DESP_HUMAN (351-874): 8.53e-10: 68.1: 8.21		UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02
+	Hs
		551869 DESP_HUMAN (351-874): 8.53e-10: 68.1: 8.21		UBP22_HUMAN (462-854): 5.81e-86: 291: 12.30
+	Hs
		1313659 MACF1_HUMAN (3704-4616): 3.72e-10: 69.3: 14.92		KTNB1_HUMAN (44-520): 3.36e-83: 287: 15.07