HitPredict

Interactor 1: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Interactor 2: SYNPO (Q8N3V7)
Synaptopodin
Gene: SYNPO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030018 - Z disc
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 4684 Hs			1 929
+	Hs
		521576 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00
+	Hs
		993296 ACTN3_HUMAN (166-893): 2.36e-146: 484: 25.79		SYP2L_HUMAN (391-924): 7.17e-28: 123: 22.96
+	Hs
		521616 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		SYP2L_HUMAN (391-924): 7.17e-28: 123: 22.96
+	Hs
		164638 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00
+	Hs
		963367 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		SYNPO_HUMAN (14-929): 5.01e-115: 376: 100.00
+	Hs
		521599 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24
+	Hs
		885297 EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75		CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24
+	Dm
		54271 A1Z9I8_DROME (337-2581): 1.27e-34: 150: 10.41		Q9VLS7_DROME (7-866): 6.18e-15: 82: 9.37
+	Hs
		963358 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		MICA3_HUMAN (231-870): 4.24e-27: 121: 12.97
+	Hs
		963398 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24
+	Hs
		551812 DESP_HUMAN (351-874): 8.53e-10: 68.1: 8.21		CIC_HUMAN (71-922): 9.17e-10: 65.1: 8.24