HitPredict

Interactor 1: Q15156 (Q15156)
PML-RAR protein
Gene: PML-RAR

Interactor 2: MBD1 (Q9UIS9)
Methyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1)
Gene: MBD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	16432238
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 797 Hs			1 605
+	Hs
		488032 RARA_HUMAN (350-797): 2.03e-106: 336: 90.40		MBD1_HUMAN (1-605): 0: 886: 100.00
+	Hs
		370660 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		MBD1_HUMAN (1-605): 0: 886: 100.00
+	Hs
		782694 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		KMT2B_HUMAN (220-385): 1.62e-39: 158: 23.53
+	Hs
		369449 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		KMT2A_HUMAN (203-473): 4.74e-45: 174: 23.05
+	Hs
		740559 PPARG_HUMAN (378-751): 2.01e-120: 374: 30.02		KDM2B_HUMAN (243-377): 3.11e-24: 110: 24.65
+	Hs
		782675 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		CXXC1_HUMAN (241-404): 9.69e-36: 144: 29.38
+	Hs
		668612 PML_HUMAN (1-413): 7.06e-89: 301: 96.37		KMT2A_HUMAN (203-473): 4.74e-45: 174: 23.05
+	Hs
		370701 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		KMT2B_HUMAN (220-385): 1.62e-39: 158: 23.53
+	Hs
		669075 PML_HUMAN (1-413): 7.06e-89: 301: 96.37		KMT2B_HUMAN (220-385): 1.62e-39: 158: 23.53
+	Hs
		328481 RARA_HUMAN (350-797): 2.03e-106: 336: 90.40		MBD3_HUMAN (7-69): 1.01e-29: 120: 50.79
+	Hs
		975296 ESR2_HUMAN (343-781): 1.46e-84: 280: 22.83		KMT2A_HUMAN (203-473): 4.74e-45: 174: 23.05
+	Hs
		782597 HNF4A_HUMAN (384-797): 7.78e-106: 335: 23.29		KDM2B_HUMAN (243-377): 3.11e-24: 110: 24.65
+	Hs
		328471 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		MBD3_HUMAN (7-69): 1.01e-29: 120: 50.79
+	Hs
		370616 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		MBD2_HUMAN (6-69): 3.83e-26: 112: 57.81
+	Hs
		370049 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		KDM2B_HUMAN (243-377): 3.11e-24: 110: 24.65
+	Mm
		1142742 ERR2_MOUSE (405-752): 2.18e-90: 293: 29.02		MBD3_MOUSE (7-69): 1.29e-29: 120: 50.79
+	Hs
		370756 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		KDM2A_HUMAN (243-379): 4.21e-19: 94.1: 23.03
+	Hs
		1245580 ESR2_HUMAN (343-781): 1.46e-84: 280: 22.83		KDM2B_HUMAN (243-377): 3.11e-24: 110: 24.65
+	Hs
		111475 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		J9JIF5_HUMAN (332-400): 1.86e-09: 61.7: 20.29
+	Hs
		370418 ESR1_HUMAN (336-795): 6.4e-97: 315: 20.89		CXXC4_HUMAN (332-400): 1.06e-09: 60.2: 20.29