HitPredict

Interactor 1: G5EEL3 (G5EEL3)
Nuclear Hormone Receptor family
Gene: nhr-70

Interactor 2: MEC3 (P09088)
Mechanosensory protein 3
Gene: mec-3

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 389 Ce			1 321
+	Ce
		447565 Q95QB3_CAEEL (1-389): 7.71e-102: 308: 36.74		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Ce
		447549 Q21372_CAEEL (11-383): 1.7e-90: 280: 25.00		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Ce
		106954 NH114_CAEEL (2-387): 6.97e-87: 271: 18.53		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Hs
		782510 HNF4A_HUMAN (2-387): 3.11e-99: 304: 22.28		ISL1_HUMAN (27-288): 1.71e-48: 167: 24.15
+	Hs
		490094 COT1_HUMAN (2-386): 6.38e-98: 299: 18.96		ISL1_HUMAN (27-288): 1.71e-48: 167: 24.15
+	Ce
		106955 NH114_CAEEL (2-387): 6.97e-87: 271: 18.53		LIN11_CAEEL (10-289): 2.15e-53: 181: 32.51
+	Hs
		238114 ESR2_HUMAN (2-387): 5.89e-80: 256: 17.86		LMX1B_HUMAN (1-316): 6.62e-58: 193: 21.84
+	Hs
		369297 ESR1_HUMAN (1-387): 4.09e-88: 279: 19.19		ISL1_HUMAN (27-288): 1.71e-48: 167: 24.15
+	Hs
		369306 ESR1_HUMAN (1-387): 4.09e-88: 279: 19.19		LMO4_HUMAN (10-165): 3.44e-39: 137: 18.75
+	Hs
		369176 ESR1_HUMAN (1-387): 4.09e-88: 279: 19.19		PAXI_HUMAN (2-208): 2.41e-31: 125: 15.79
+	Hs
		823459 ESR2_HUMAN (2-387): 5.89e-80: 256: 17.86		PAXI_HUMAN (2-208): 2.41e-31: 125: 15.79
+	Ce
		447563 Q86PI8_CAEEL (11-89): 7.29e-20: 90.9: 45.57		MEC3_CAEEL (1-321): 1.79e-71: 226: 100.00
+	Ce
		589697 Q86PI8_CAEEL (11-89): 7.29e-20: 90.9: 45.57		LIN11_CAEEL (10-289): 2.15e-53: 181: 32.51