HitPredict

Interactor 1: TEBP (Q15185)
Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)
Gene: PTGES3

Interactor 2: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006457 - protein folding GO:0032991 - protein-containing complex GO:0050821 - protein stabilization and 1 others more... GO:0051082 - unfolded protein binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 418
+	Hs
		1069364 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81
+	Hs
		431869 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		438187 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Mm
		513707 TEBP_MOUSE (1-160): 2.5e-54: 170: 98.75		HS90B_MOUSE (96-256): 4.94e-41: 156: 51.85
+	Hs
		538244 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		ENPL_HUMAN (96-407): 1.36e-36: 144: 26.90
+	Hs
		1069363 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		H90B4_HUMAN (112-275): 1.78e-26: 112: 42.42
+	Sc
		365919 SBA1_YEAST (3-140): 3.46e-28: 105: 22.37		HSP82_YEAST (111-258): 1.18e-42: 160: 46.62
+	Sc
		543325 SBA1_YEAST (3-140): 3.46e-28: 105: 22.37		HSC82_YEAST (111-258): 2.14e-42: 160: 46.62
+	Hs
		1069388 TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00		Q6PK50_HUMAN (96-157): 2.21e-13: 72.7: 61.91