HitPredict

Interactor 1: STK38 (Q15208)
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)
Gene: STK38

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	26527279
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 126
+	Hs
		1087429 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		325866 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		H2B1M_HUMAN (1-126): 5.38e-54: 166: 96.03
+	Hs
		1129870 MRCKB_HUMAN (64-463): 2.71e-128: 409: 41.26		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		1274489 MRCKB_HUMAN (64-463): 2.71e-128: 409: 41.26		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		617926 AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06		H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21
+	Mm
		682111 AKT1_MOUSE (50-447): 2.25e-137: 405: 27.16		H2B2B_MOUSE (1-126): 2.34e-54: 168: 97.62
+	Hs
		886228 MRCKB_HUMAN (64-463): 2.71e-128: 409: 41.26		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		420806 AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		617927 AKT2_HUMAN (6-447): 2.1e-137: 405: 24.45		H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21
+	Hs
		681878 AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		420807 AKT2_HUMAN (6-447): 2.1e-137: 405: 24.45		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		681686 AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Mm
		682113 AKT1_MOUSE (50-447): 2.25e-137: 405: 27.16		H2B1C_MOUSE (1-126): 1.18e-53: 166: 99.21
+	Hs
		682181 AKT2_HUMAN (6-447): 2.1e-137: 405: 24.45		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		682137 AKT2_HUMAN (6-447): 2.1e-137: 405: 24.45		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		681937 AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06		H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03
+	Hs
		682194 AKT2_HUMAN (6-447): 2.1e-137: 405: 24.45		H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03
+	Hs
		610760 KAPCB_HUMAN (74-418): 6.95e-128: 376: 34.29		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		610687 KAPCB_HUMAN (74-418): 6.95e-128: 376: 34.29		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		610761 KAPCB_HUMAN (74-418): 6.95e-128: 376: 34.29		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04