HitPredict

Interactor 1: STK38 (Q15208)
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)
Gene: STK38

Interactor 2: MOB1B (Q7L9L4)
MOB kinase activator 1B (Mob1 homolog 1A) (Mob1A) (Mob1B) (Mps one binder kinase activator-like 1A)
Gene: MOB1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.735

Property	Details
Experiments	28514442, 33961781, 37536630, 19919647, 32707033, 15067004
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 216
+	Hs
		1069652 STK38_HUMAN (1-465): 0: 527: 100.00		MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83
+	Hs
		1185506 ST38L_HUMAN (11-465): 5.84e-178: 508: 87.47		MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00
+	Hs
		1333714 ST38L_HUMAN (11-465): 5.84e-178: 508: 87.47		MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83
+	Hs
		1185503 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00
+	Hs
		1333705 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83
+	Dm
		1278869 TRC_DROME (13-454): 7.98e-159: 459: 70.00		MOB1_DROME (1-216): 7.76e-116: 330: 87.96
+	Hs
		325787 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00
+	Hs
		1069621 STK38_HUMAN (1-465): 0: 527: 100.00		MOB2_HUMAN (1-213): 4e-86: 256: 40.85
+	Hs
		1198336 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		MOB3B_HUMAN (5-212): 3.49e-108: 311: 53.59
+	Hs
		1174241 ST38L_HUMAN (11-465): 5.84e-178: 508: 87.47		MOB2_HUMAN (1-213): 4e-86: 256: 40.85
+	Hs
		1285989 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		MOB3A_HUMAN (5-212): 3.88e-106: 306: 53.11
+	Hs
		1174306 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		MOB3C_HUMAN (5-212): 1.7e-105: 304: 48.80
+	Hs
		325791 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		MOB3B_HUMAN (5-212): 3.49e-108: 311: 53.59
+	Hs
		325785 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		MOB3C_HUMAN (5-212): 1.7e-105: 304: 48.80
+	Sp
		140739 ORB6_SCHPO (3-457): 2.03e-161: 466: 48.81		MOB2_SCHPO (14-215): 2.45e-87: 259: 39.60
+	Ca
		1124241 CBK1_CANAL (3-457): 1.24e-155: 460: 47.33		MOB2_CANAL (25-216): 4.12e-88: 263: 41.15
+	Sc
		774485 CBK1_YEAST (3-457): 1.36e-154: 458: 46.23		MOB1_YEAST (7-214): 2.04e-84: 254: 49.05
+	Sc
		797131 CBK1_YEAST (3-457): 1.36e-154: 458: 46.23		MOB2_YEAST (17-216): 3.01e-82: 247: 37.50
+	Hs
		325784 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		MOB2_HUMAN (1-213): 4e-86: 256: 40.85
+	Hs
		1344983 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		PHOCN_HUMAN (6-201): 3.76e-67: 207: 19.60