HitPredict

Interactor 1: NH114 (G5EEM0)
Nuclear hormone receptor 114
Gene: nhr-114

Interactor 2: NHR43 (Q18299)
Nuclear hormone receptor family member nhr-43
Gene: nhr-43

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms	GO:0004879 - nuclear receptor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Ce			1 449
+	Ce
		106935 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		H2KZA1_CAEEL (13-442): 4.98e-77: 252: 17.59
+	Ce
		106933 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		NH114_CAEEL (34-448): 6.54e-78: 250: 14.55
+	Ce
		106915 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		G5EEL3_CAEEL (37-449): 1.42e-76: 245: 16.91
+	Ce
		106938 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		H2L0B0_CAEEL (46-448): 1.8e-75: 243: 19.27
+	Ce
		106987 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		Q8MXK0_CAEEL (34-445): 1.42e-73: 239: 17.68
+	Ce
		106951 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		NHR49_CAEEL (19-442): 7.24e-71: 234: 16.51
+	Ce
		785440 NHR10_CAEEL (2-411): 1.62e-108: 326: 55.23		NHR10_CAEEL (30-448): 1.19e-79: 254: 14.05
+	Hs
		587112 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59
+	Hs
		368969 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		ESR1_HUMAN (8-443): 1.02e-75: 249: 12.75
+	Hs
		587136 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		RXRG_HUMAN (1-449): 7.24e-76: 246: 12.42
+	Mm
		659690 RXRA_MOUSE (3-409): 1.65e-101: 311: 22.30		NR1H3_MOUSE (4-446): 1.21e-74: 242: 13.09
+	Hs
		500354 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		RARB_HUMAN (5-449): 1.49e-72: 237: 14.38
+	Hs
		265850 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		NR1I2_HUMAN (33-445): 5.11e-72: 235: 15.13
+	Hs
		530782 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		RARG_HUMAN (3-233): 8.6e-54: 188: 23.14
+	Mm
		509288 RXRA_MOUSE (3-409): 1.65e-101: 311: 22.30		RARA_MOUSE (12-233): 6.13e-51: 180: 21.46
+	Hs
		487899 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		RARA_HUMAN (12-233): 1.33e-51: 182: 21.89
+	Ce
		106970 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		Q19496_CAEEL (45-153): 3.8e-11: 67: 36.70
+	Mm
		613149 RXRA_MOUSE (3-409): 1.65e-101: 311: 22.30		PPARA_MOUSE (32-152): 2.61e-10: 64.3: 33.07
+	Mm
		659673 RXRA_MOUSE (3-409): 1.65e-101: 311: 22.30		PPARG_MOUSE (5-130): 5.53e-10: 63.2: 30.56
+	Hs
		587130 RXRA_HUMAN (3-409): 2.8e-100: 308: 22.30		PPARG_HUMAN (5-130): 4.55e-10: 63.5: 30.56