HitPredict

Interactor 1: STK38 (Q15208)
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)
Gene: STK38

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16884686
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 1024
+	Hs
		1069657 STK38_HUMAN (1-465): 0: 527: 100.00		SMUF1_HUMAN (593-1024): 1.71e-157: 485: 23.71
+	Hs
		1336122 ST38L_HUMAN (11-465): 5.84e-178: 508: 87.47		SMUF1_HUMAN (593-1024): 1.71e-157: 485: 23.71
+	Hs
		808286 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		NEDD4_HUMAN (652-1023): 3.7e-161: 511: 26.04
+	Hs
		325886 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		WWP1_HUMAN (588-1024): 8.35e-169: 520: 21.93
+	Hs
		125071 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		WWP2_HUMAN (599-1024): 1.14e-167: 516: 22.02
+	Hs
		325655 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		NEDD4_HUMAN (652-1023): 3.7e-161: 511: 26.04
+	Hs
		325853 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		ITCH_HUMAN (593-1024): 1.76e-165: 511: 24.22
+	Hs
		325894 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		SMUF2_HUMAN (648-1024): 5.74e-160: 491: 26.22
+	Hs
		325898 LATS1_HUMAN (7-448): 7.81e-146: 446: 40.48		SMUF1_HUMAN (593-1024): 1.71e-157: 485: 23.71
+	Hs
		681731 AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06		NEDD4_HUMAN (652-1023): 3.7e-161: 511: 26.04
+	Hs
		808324 AKT3_HUMAN (37-447): 1.08e-137: 406: 27.83		NEDD4_HUMAN (652-1023): 3.7e-161: 511: 26.04
+	Hs
		1299664 AKT3_HUMAN (37-447): 1.08e-137: 406: 27.83		NED4L_HUMAN (652-1023): 2.49e-164: 510: 28.13
+	Hs
		681988 AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06		NED4L_HUMAN (652-1023): 2.49e-164: 510: 28.13
+	Hs
		568634 KAPCA_HUMAN (59-418): 5.12e-128: 376: 33.15		UBE3A_HUMAN (414-1024): 1.12e-172: 529: 25.37
+	Dm
		1360297 WARTS_DROME (19-462): 1.96e-139: 429: 43.27		SMUF1_DROME (665-1024): 3.72e-148: 470: 26.06
+	Hs
		568765 KAPCA_HUMAN (59-418): 5.12e-128: 376: 33.15		ITCH_HUMAN (593-1024): 1.76e-165: 511: 24.22
+	Hs
		1035209 ROCK1_HUMAN (70-415): 3.59e-79: 270: 42.90		SMUF1_HUMAN (593-1024): 1.71e-157: 485: 23.71
+	Hs
		1218012 LATS2_HUMAN (5-465): 2.49e-150: 457: 40.58		HERC6_HUMAN (7-207): 4.36e-23: 108: 15.21