HitPredict

Interactor 1: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Interactor 2: PAN2 (Q504Q3)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23398456
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006397 - mRNA processing
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 471 Hs			1 1202
+	Hs
		1031353 PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42		PAN2_HUMAN (1-1202): 0: 1136: 100.00
+	Hs
		516542 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		PAN2_HUMAN (1-1202): 0: 1136: 100.00
+	Hs
		613477 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		PAN2_HUMAN (1-1202): 0: 1136: 100.00
+	Hs
		1077385 ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82		PAN2_HUMAN (1-1202): 0: 1136: 100.00
+	Sc
		376857 PABP_YEAST (30-384): 3.77e-37: 145: 16.50		PAN2_YEAST (71-1186): 5.22e-176: 550: 22.50
+	Hs
		516625 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		UBP7_HUMAN (340-1038): 1.3e-89: 315: 12.02
+	Hs
		516747 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		UBP22_HUMAN (462-854): 5.81e-86: 291: 12.30
+	Sc
		376803 PABP_YEAST (30-384): 3.77e-37: 145: 16.50		UTP7_YEAST (35-461): 8e-81: 278: 15.37
+	Hs
		1263542 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		I20L2_HUMAN (971-1156): 1.7e-54: 196: 24.23
+	Hs
		171763 ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81		WDR46_HUMAN (35-483): 2.12e-94: 317: 12.19
+	Hs
		69578 ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81		B0UZZ8_HUMAN (35-483): 2.12e-94: 317: 12.19
+	Hs
		1220120 PABP5_HUMAN (78-205): 4.72e-26: 111: 26.76		GOR_HUMAN (951-1156): 1.52e-46: 180: 21.91
+	Hs
		1308761 RBM4B_HUMAN (75-182): 7.1e-09: 59.3: 35.71		REXO4_HUMAN (935-1156): 1.81e-56: 203: 27.19
+	Hs
		1314613 RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71		REXO4_HUMAN (935-1156): 1.81e-56: 203: 27.19