HitPredict

Interactor 1: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 16169070, 32296183, 24981860, 35271311, 21819346, 25416956, 28514442, 33961781, 34017080, 35235311, 37071682, 22416126, 16148043, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, x-ray crystallography, anti tag coimmunoprecipitation, pull down, molecular sieving, x ray scattering, two hybrid prey pooling approach, two hybrid array and 3 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOPS~NOPS, NOPS~RRM_1, RRM_1~RRM_1
Common GO terms GO:0001650 - fibrillar center
GO:0002218 - activation of innate immune response
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 7 others

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Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 471
Hs

1 523
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Last updated: 15 Jul 2024