HitPredict

Interactor 1: NH114 (G5EEM0)
Nuclear hormone receptor 114
Gene: nhr-114

Interactor 2: EGL43 (Q22024)
Zinc finger protein egl-43 (Egg-laying defective protein 43)
Gene: egl-43

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 418 Ce			1 543
+	Ce
		220337 NHR49_CAEEL (13-409): 1.14e-94: 294: 24.88		EGL43_CAEEL (1-543): 0: 579: 100.00
+	Ce
		1094603 Q86PI8_CAEEL (1-287): 1.68e-92: 282: 99.65		EGL43_CAEEL (1-543): 0: 579: 100.00
+	Ce
		999486 NHR22_CAEEL (2-406): 1.82e-85: 273: 22.49		EGL43_CAEEL (1-543): 0: 579: 100.00
+	Hs
		1269362 ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25		ZN845_HUMAN (73-542): 2.67e-128: 399: 15.72
+	Ce
		1088801 NHR47_CAEEL (297-418): 5.1e-09: 60.1: 26.02		EGL43_CAEEL (1-543): 0: 579: 100.00
+	Hs
		782648 HNF4A_HUMAN (4-413): 1.1e-90: 283: 21.95		ZN471_HUMAN (98-542): 1.58e-111: 346: 18.00
+	Hs
		824153 NR2C2_HUMAN (1-406): 2.97e-88: 281: 17.39		ZN546_HUMAN (261-542): 2.09e-98: 318: 17.19
+	Hs
		563312 ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25		ZNF16_HUMAN (290-541): 1.08e-71: 243: 15.47
+	Ce
		106996 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		LSY2_CAEEL (144-231): 1.2e-13: 74.3: 45.06
+	Ce
		106388 NH114_CAEEL (1-418): 2.64e-131: 385: 100.00		OVOLH_CAEEL (443-495): 7.16e-11: 65.1: 50.94
+	Hs
		1239545 ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25		ZFP62_HUMAN (1-104): 9.58e-27: 117: 13.33
+	Mm
		56931 COT2_MOUSE (4-413): 1.43e-95: 294: 18.05		PRD16_MOUSE (67-243): 1.02e-19: 95.5: 36.22
+	Ce
		106392 NHR49_CAEEL (13-409): 1.14e-94: 294: 24.88		OVOLH_CAEEL (443-495): 7.16e-11: 65.1: 50.94
+	Ce
		106401 Q86PI8_CAEEL (1-287): 1.68e-92: 282: 99.65		OVOLH_CAEEL (443-495): 7.16e-11: 65.1: 50.94
+	Ce
		1089861 NHR31_CAEEL (2-411): 1.41e-82: 265: 24.40		LSY2_CAEEL (144-231): 1.2e-13: 74.3: 45.06
+	Ce
		106394 NHR22_CAEEL (2-406): 1.82e-85: 273: 22.49		OVOLH_CAEEL (443-495): 7.16e-11: 65.1: 50.94
+	Ce
		106395 NHR31_CAEEL (2-411): 1.41e-82: 265: 24.40		OVOLH_CAEEL (443-495): 7.16e-11: 65.1: 50.94