HitPredict

Interactor 1: NH114 (G5EEM0)
Nuclear hormone receptor 114
Gene: nhr-114

Interactor 2: EGL13 (Q23045)
Transcription factor egl-13 (Protein egg laying defective 13)
Gene: egl-13

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Ce			1 470
+	Ce
		109789 H2KZA1_CAEEL (5-416): 4.62e-91: 288: 22.86		EGL13_CAEEL (1-470): 0: 553: 100.00
+	Ce
		1095161 Q86PI8_CAEEL (1-287): 1.68e-92: 282: 99.65		EGL13_CAEEL (1-470): 0: 553: 100.00
+	Hs
		233806 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		HBP1_HUMAN (150-408): 1.95e-51: 183: 23.27
+	Hs
		490111 COT1_HUMAN (2-413): 4.92e-100: 306: 18.93		CIC_HUMAN (183-464): 5.04e-36: 144: 17.00
+	Hs
		370101 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		BBX_HUMAN (308-470): 2.05e-40: 156: 20.83
+	Hs
		1264299 ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25		BBX_HUMAN (308-470): 2.05e-40: 156: 20.83
+	Hs
		622826 COT2_HUMAN (4-413): 1.43e-95: 294: 18.05		CIC_HUMAN (183-464): 5.04e-36: 144: 17.00
+	Hs
		370251 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		CIC_HUMAN (183-464): 5.04e-36: 144: 17.00
+	Hs
		1301017 NR2E1_HUMAN (1-406): 6.75e-93: 286: 23.13		CIC_HUMAN (183-464): 5.04e-36: 144: 17.00
+	Mm
		587110 ESR1_MOUSE (7-418): 2.5e-89: 284: 21.91		TF7L1_MOUSE (189-457): 1.24e-36: 143: 14.39
+	Hs
		782638 HNF4A_HUMAN (4-413): 1.1e-90: 283: 21.95		CIC_HUMAN (183-464): 5.04e-36: 144: 17.00
+	Hs
		1269413 ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25		CIC_HUMAN (183-464): 5.04e-36: 144: 17.00
+	Hs
		782669 HNF4A_HUMAN (4-413): 1.1e-90: 283: 21.95		TF7L2_HUMAN (189-433): 1.49e-35: 141: 17.55
+	Hs
		1269929 ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25		SOX13_HUMAN (222-448): 3.16e-34: 137: 37.00
+	Hs
		370492 ESR1_HUMAN (7-417): 1.23e-90: 287: 21.96		HM20A_HUMAN (232-425): 3.19e-33: 130: 13.33
+	Mm
		587094 ESR1_MOUSE (7-418): 2.5e-89: 284: 21.91		LEF1_MOUSE (206-423): 5.32e-34: 133: 17.89
+	Mm
		703486 STF1_MOUSE (9-411): 3.34e-91: 284: 19.83		SOX8_MOUSE (238-421): 2.96e-33: 132: 27.81
+	Hs
		817785 NR2C2_HUMAN (1-406): 2.97e-88: 281: 17.39		SOX2_HUMAN (292-418): 2.19e-34: 132: 40.95
+	Hs
		1269686 ESR2_HUMAN (2-406): 1.91e-89: 282: 23.25		HM20A_HUMAN (232-425): 3.19e-33: 130: 13.33
+	Mm
		703482 STF1_MOUSE (9-411): 3.34e-91: 284: 19.83		SOX2_MOUSE (292-418): 7.43e-33: 128: 40.31