HitPredict

Interactor 1: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Interactor 2: RBM7 (Q9Y580)
RNA-binding protein 7 (RNA-binding motif protein 7)
Gene: RBM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 471 Hs			1 266
+	Mm
		1207997 NONO_MOUSE (1-471): 4.7e-94: 294: 98.31		CSTFT_MOUSE (3-157): 5.11e-22: 97.1: 22.56
+	Hs
		516495 PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		613630 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		RBM7_HUMAN (1-266): 2.96e-58: 188: 100.00
+	Hs
		1031404 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		PABP4_HUMAN (4-262): 1.83e-39: 146: 15.14
+	Hs
		516608 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		516339 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		PABP1_HUMAN (4-256): 1.02e-38: 144: 14.71
+	Hs
		474021 PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42		PAB4L_HUMAN (4-171): 1.42e-33: 126: 14.52
+	Hs
		516689 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		PABP3_HUMAN (11-256): 9.43e-37: 139: 13.81
+	Hs
		516471 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		TIAR_HUMAN (2-205): 1.07e-30: 119: 16.30
+	Hs
		1020249 PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Ce
		71809 B3GWA1_CAEEL (67-335): 1.39e-73: 243: 44.98		O45577_CAEEL (2-123): 1.8e-19: 87.9: 26.83
+	Hs
		1020299 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Hs
		516484 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		ELAV2_HUMAN (2-205): 9.2e-23: 97.4: 16.09
+	Mm
		857359 PSPC1_MOUSE (20-470): 5.48e-67: 225: 57.40		TIA1_MOUSE (3-187): 3.59e-16: 79: 14.21
+	Hs
		1073607 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		SF3B4_HUMAN (7-242): 3.59e-15: 76.6: 15.39
+	Mm
		665745 PABP1_MOUSE (66-459): 9.31e-65: 222: 14.89		TIA1_MOUSE (3-187): 3.59e-16: 79: 14.21
+	Xl
		1265032 ELAV2_XENLA (40-205): 1.41e-56: 194: 25.82		ELAV2_XENLA (2-91): 5.32e-23: 98.6: 28.57
+	Hs
		613467 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		SF3B4_HUMAN (7-242): 3.59e-15: 76.6: 15.39