HitPredict

Interactor 1: PTPRK (Q15262)
Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)
Gene: PTPRK

Interactor 2: LRP1B (Q9NZR2)
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)
Gene: LRP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EGF_CA~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1439 Hs			1 4599
+	Hs
		1048400 PTPRK_HUMAN (26-1439): 0: 1191: 100.00		NID2_HUMAN (4360-4522): 5.4e-12: 74.9: 10.66
+	Hs
		577015 PTPRA_HUMAN (668-1438): 0: 736: 30.62		NOTC2_HUMAN (11-260): 3.49e-09: 66: 14.40
+	Hs
		537520 PTPRO_HUMAN (1162-1433): 5.11e-94: 333: 30.22		NID1_HUMAN (3473-3718): 1.32e-09: 67.1: 13.83
+	Hs
		489894 PTPRF_HUMAN (194-928): 2.83e-47: 188: 10.24		NID1_HUMAN (3473-3718): 1.32e-09: 67.1: 13.83