Interactor 1: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1
Interactor 2: RABX5 (Q9UJ41)
Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)
Gene: RABGEF1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24957337, 26430212, 28514442, 33961781, 17341663, 9323142, 35271311, 10720461, 11452015, 17450153 |
| Identification Methods | x-ray crystallography, pull down, affinity chromatography technology, biochemical, fluorescence polarization spectroscopy, anti tag coimmunoprecipitation |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Rab5-bind~VPS9 |
| Common GO terms | GO:0005769 - early endosome GO:0015031 - protein transport GO:0030139 - endocytic vesicle GO:0031901 - early endosome membrane GO:0055037 - recycling endosome |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
