HitPredict

Interactor 1: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1

Interactor 2: RAB21 (Q9UL25)
Ras-related protein Rab-21
Gene: RAB21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Rab5-bind~Ras
Common GO terms	GO:0005768 - endosome GO:0005769 - early endosome GO:0031901 - early endosome membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 862 Hs			1 225
+	Hs
		918873 RABE1_HUMAN (1-862): 6.85e-68: 244: 100.00		RAB1A_HUMAN (9-222): 6.14e-87: 257: 32.24
+	Hs
		914082 RABE1_HUMAN (1-862): 6.85e-68: 244: 100.00		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Hs
		844533 RABE1_HUMAN (1-862): 6.85e-68: 244: 100.00		RAB5C_HUMAN (1-224): 1.01e-51: 168: 39.82
+	Hs
		592268 RABE1_HUMAN (1-862): 6.85e-68: 244: 100.00		RAB5A_HUMAN (10-224): 2.26e-49: 162: 41.28
+	Hs
		148636 CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86		RAB1A_HUMAN (9-222): 6.14e-87: 257: 32.24
+	Hs
		149274 CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86		RAB1B_HUMAN (12-222): 1.28e-85: 254: 30.81
+	Dm
		1358755 Q9W2M0_DROME (296-843): 3.47e-39: 157: 20.80		RAB5_DROME (6-203): 4.32e-47: 156: 41.75
+	Hs
		592497 RABE2_HUMAN (51-217): 5.05e-20: 96.7: 46.11		RAB5A_HUMAN (10-224): 2.26e-49: 162: 41.28
+	Hs
		148389 CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86		RAB5A_HUMAN (10-224): 2.26e-49: 162: 41.28
+	Hs
		148551 CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86		RAB13_HUMAN (20-200): 1.67e-42: 144: 38.67