HitPredict

Interactor 1: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Interactor 2: SYF1 (Q9HCS7)
Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2)
Gene: XAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006351 - DNA-templated transcription
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 855
+	Hs
		1336499 PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73		SYF1_HUMAN (1-855): 0: 602: 100.00
+	Sc
		978483 NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46		SYF1_YEAST (19-733): 1.86e-87: 298: 22.31
+	Hs
		1070619 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		1318165 PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		174907 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		1063203 SART3_HUMAN (2-302): 1.67e-38: 146: 16.32		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		174461 RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		1022281 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		CSTF3_HUMAN (11-543): 2.99e-35: 145: 13.25
+	Hs
		1063207 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Mm
		665754 PABP1_MOUSE (65-252): 1.7e-21: 96.5: 16.32		CTR9_MOUSE (44-847): 2.92e-40: 162: 11.34
+	Hs
		174583 PABP1_HUMAN (65-252): 1.33e-21: 96.9: 16.32		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		300152 RNPS1_HUMAN (1-234): 2e-34: 128: 100.00		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		174849 PABP4_HUMAN (153-248): 4.98e-19: 89.2: 27.08		OGT1_HUMAN (7-468): 1.59e-37: 154: 13.55
+	Hs
		300288 PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		300087 NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Ce
		954283 Q9U2S6_CAEEL (156-263): 5.51e-20: 90.4: 20.37		P91175_CAEEL (1-617): 1.55e-26: 118: 12.50
+	Dm
		54167 PPIE_DROME (157-291): 2.07e-31: 120: 18.52		SYF1_DROME (1-255): 9.35e-16: 83.9: 13.69
+	Sc
		982907 NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46		RRP5_YEAST (507-723): 1.31e-11: 70.9: 15.46
+	Sc
		996591 NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46		CLF1_YEAST (3-250): 5.35e-11: 68.5: 12.06