HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: CYTSB (Q5M775)
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)
Gene: SPECC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31076518, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 1068
+	Hs
		865142 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		SMTN_HUMAN (750-1067): 9.99e-35: 145: 22.26
+	Hs
		64595 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		MYH7B_HUMAN (563-956): 7.08e-09: 62.6: 12.09
+	Hs
		903285 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		865154 NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38		SMTN_HUMAN (750-1067): 9.99e-35: 145: 22.26
+	Hs
		1189782 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		MYH14_HUMAN (366-799): 4.09e-49: 193: 20.33
+	Hs
		903334 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		MYH14_HUMAN (366-799): 4.09e-49: 193: 20.33
+	Hs
		728492 POC1A_HUMAN (145-538): 3.26e-45: 165: 10.89		MYH11_HUMAN (487-993): 4.15e-16: 86.1: 11.83
+	Hs
		725215 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Hs
		1240468 POC1A_HUMAN (145-538): 3.26e-45: 165: 10.89		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Hs
		724952 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		1148943 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		CYTSA_HUMAN (1-389): 7.43e-11: 68.7: 7.36