HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	19131338
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 538 Hs			1 1322
+	Hs
		1190862 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		EMSY_HUMAN (1-1322): 5.68e-132: 441: 100.00
+	Hs
		1070759 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		MINT_HUMAN (72-1304): 8.31e-15: 82.4: 10.57
+	Hs
		1070746 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		KMT2C_HUMAN (136-1005): 1.04e-12: 75.6: 6.91
+	Hs
		152650 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		152663 WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		1302927 NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38		MINT_HUMAN (72-1304): 8.31e-15: 82.4: 10.57
+	Hs
		1056932 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		1147485 NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		1056974 WDR33_HUMAN (198-342): 2.09e-17: 88.1: 10.67		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		1281391 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		PRR36_HUMAN (374-1319): 5.2e-26: 118: 9.73
+	Hs
		297832 BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86		K0754_HUMAN (478-1064): 5.31e-21: 102: 10.83
+	Hs
		1288258 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		MINT_HUMAN (72-1304): 8.31e-15: 82.4: 10.57
+	Hs
		1264784 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		1102997 SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Hs
		72754 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		B4DET5_HUMAN (148-938): 2.35e-12: 73.7: 12.66
+	Hs
		1147471 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		152678 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Hs
		1288235 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		P121A_HUMAN (148-938): 9.85e-10: 65.6: 12.45
+	Hs
		1192155 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Hs
		152622 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65