HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: WDR24 (Q96S15)
GATOR2 complex protein WDR24 (EC 2.3.2.27) (WD repeat-containing protein 24)
Gene: WDR24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 790
+	Hs
		1070727 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		WDR59_HUMAN (159-345): 6.31e-21: 100: 20.31
+	Hs
		1070791 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		MIOS_HUMAN (2-326): 4.54e-17: 87.9: 13.22
+	Hs
		903242 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		WDR5_HUMAN (1-102): 2.39e-12: 71: 14.42
+	Hs
		1070736 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		WDR5B_HUMAN (1-102): 3.59e-12: 70.2: 15.39
+	Mm
		903670 RBBP5_MOUSE (1-538): 9.56e-137: 408: 99.07		WDR5_MOUSE (1-102): 2.39e-12: 71: 14.42
+	Dr
		1193337 Q7ZUU9_DANRE (1-506): 1.49e-116: 355: 89.02		Q7ZTX2_DANRE (1-102): 5.5e-12: 69.8: 14.42
+	Hs
		792935 LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65		LIS1_HUMAN (2-284): 6.34e-64: 221: 13.91
+	Hs
		1240442 POC1B_HUMAN (2-186): 2.12e-49: 179: 17.74		POC1A_HUMAN (1-281): 4.63e-64: 221: 16.73
+	Sc
		763533 SWD1_YEAST (1-356): 1.48e-77: 252: 30.08		PFS2_YEAST (12-289): 6.3e-29: 122: 17.38
+	Hs
		793026 LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65		KTNB1_HUMAN (2-155): 1.19e-26: 117: 12.99
+	Ca
		483033 TUP1_CANAL (100-402): 3.81e-53: 190: 16.10		TUP1_CANAL (244-449): 4.18e-22: 102: 9.91
+	Hs
		903349 WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88		WDR5_HUMAN (1-102): 2.39e-12: 71: 14.42
+	Hs
		1202778 WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88		GRWD1_HUMAN (116-272): 1.12e-10: 66.6: 25.00
+	Hs
		792949 LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65		WDR5_HUMAN (1-102): 2.39e-12: 71: 14.42
+	Hs
		1346954 NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38		NLE1_HUMAN (280-564): 1.09e-27: 119: 10.36
+	Mm
		925836 LIS1_MOUSE (104-423): 6.46e-53: 186: 9.65		LIS1_MOUSE (370-592): 1.08e-09: 63.3: 7.50
+	Hs
		1288273 WDR83_HUMAN (1-327): 4.72e-39: 146: 20.61		SNR40_HUMAN (1-147): 3.53e-22: 101: 16.00
+	Sc
		630844 NLE1_YEAST (106-430): 1.32e-45: 169: 7.49		NLE1_YEAST (332-538): 1.04e-13: 76.3: 8.48
+	Hs
		903551 NLE1_HUMAN (2-135): 8.57e-34: 135: 18.38		WDR5_HUMAN (1-102): 2.39e-12: 71: 14.42