HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: KAT8 (Q9H7Z6)
Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (Males-absent on the first protein homolog) (hMOF) (Protein acetyltransferase KAT8) (EC 2.3.1.-) (Protein propionyltransferase KAT8) (EC 2.3.1.-)
Gene: KAT8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	15960975, 24981860
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045815 - transcription initiation-coupled chromatin remodeling GO:0071339 - MLL1 complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 458
+	Hs
		903522 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		KAT8_HUMAN (14-458): 0: 733: 100.00
+	Dm
		137457 WDS_DROME (250-438): 1.02e-21: 98.5: 10.82		MOF_DROME (59-453): 0: 548: 52.85
+	Hs
		309739 WDR33_HUMAN (198-342): 2.09e-17: 88.1: 10.67		KAT7_HUMAN (85-450): 2.43e-177: 511: 45.59
+	Hs
		309726 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		KAT7_HUMAN (85-450): 2.43e-177: 511: 45.59
+	Hs
		1270865 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		KAT6A_HUMAN (59-447): 1.57e-142: 451: 42.31
+	Hs
		903406 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		KAT6A_HUMAN (59-447): 1.57e-142: 451: 42.31