HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: ASH2L (Q9UBL3)
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)
Gene: ASH2L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 23870121, 26886794, 15199122, 31076518, 31544921, 23414517, 34079125, 23508102, 16253997, 37974198, 19131338, 17925232, 17500065, 21285357, 16603732, 21124902, 20305087, 25416956, 21516116, 32296183 and 9 others

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Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology, isothermal titration calorimetry, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation and 3 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0035097 - histone methyltransferase complex
and 6 others

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Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 538
Hs

1 628
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024