HitPredict

Interactor 1: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Interactor 2: KDM2A (Q9Y2K7)
Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)
Gene: KDM2A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 1162
+	Hs
		1288397 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		KDM2A_HUMAN (1-1162): 0: 1354: 100.00
+	Hs
		903622 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		KDM2A_HUMAN (1-1162): 0: 1354: 100.00
+	Mm
		903667 WDR5_MOUSE (282-429): 2.1e-09: 61.2: 11.41		KDM2B_MOUSE (1-1162): 0: 1038: 37.73
+	Hs
		1127484 WDR44_HUMAN (53-281): 4.14e-54: 198: 24.46		FXL19_HUMAN (538-1145): 3.09e-133: 423: 35.96
+	Hs
		1288392 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Mm
		876680 RBBP5_MOUSE (1-538): 9.56e-137: 408: 99.07		KMT2A_MOUSE (360-609): 1.12e-50: 199: 20.73
+	Hs
		975258 RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		903608 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		975304 SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		975303 FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		903149 WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Dm
		1279320 EBI_DROME (179-518): 9.89e-30: 125: 10.98		JHD1_DROME (431-568): 5.89e-28: 124: 27.54