Interactor 1: ERBB4 (Q15303)
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]
Gene: ERBB4

Interactor 2: LRIG1 (Q96JA1)
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1)
Gene: LRIG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.871

The method score is based on:

Property Details
Experiments 20126551, 15345710, 15282549
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains GF_recep_IV~LRR_4, GF_recep_IV~LRR_8, LRR_4~PK_Tyr_Ser-Thr, LRR_8~PK_Tyr_Ser-Thr
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1308
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Last updated: 15 Jul 2024